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KMID : 0360220140550020252
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Journal of the Korean Ophthalmological Society
2014 Volume.55 No. 2 p.252 ~ p.260
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Long-Term Outcomes of Trabeculectomy in Korean Patients with Juvenile Open-Angle Glaucoma
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Oh Eun-Kyu
Lee Eun-Ji
Jeong Jin-Wook
Kim Seok-Hwan
Kim Tae-Woo
Park Ki-Ho
Kim Dong-Myoung
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Abstract
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Purpose: To evaluate the outcomes and prognostic factors of trabeculectomy with mitomycin C in Korean patients with juvenile open-angle glaucoma (JOAG).
Methods: A retrospective review was performed on 29 eyes with JOAG who had undergone trabeculectomy between January 2004 and January 2013. Intraocular pressure (IOP) and postoperative complications were monitored at 1 day preoperatively, at 1 day, 1 week, 1 month, 3 months, 6 months, and 12 months postoperatively, and at final follow-up after postoperative 18 months. Surgical success was defined as a final IOP of <21 mm Hg or <80% of preoperative IOP, regardless of the use of anti-glaucoma medication. Prognostic factors for surgical success or failure were analyzed by the Cox proportional hazards model.
Results: Mean (± standard deviation) age at trabeculectomy was 24.6 (± 8.9) years, and mean follow-up period was 24.3 (± 20.8) months. The overall success rate was 82.8% at final follow-up. The Kaplan-Meier cumulative probabilities of surgical success were 100% at 1 year, 87.4% at 2 years, and 78.7% at 3 years postoperatively. The Cox proportional hazards model failed to determine any significant factors that were associated with surgical failure. The three most frequent postoperative complications were immediately postoperative hypotony (n = 19, 65.5%), hypotony maculopathy (n = 8, 27.6%), and encapsulated bleb (n = 8, 27.6%), most of which were resolved after a minor procedure or observation. Two of 8 eyes with encapsulated bleb required a second surgery. There were no vision-threatening severe complications.
Conclusions: Trabeculectomy with MMC may be an effective treatment in Korean JOAG patients.
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KEYWORD
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Juvenile open-angle glaucoma, Prognostic factor, Surgical outcomes, Trabeculectomy
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